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Orphenadrine: what it is, what it is for and how to use it

Orphenadrine or Orphenadrine Citrate is a muscle relaxant indicated for pain caused by muscle contractions, sprains or strains, or tension headache, helping to relieve discomfort. This remedy is usually associated with dipyrone or paracetamol, which have analgesic action, and with caffeine, which enhances the relaxing and anti-inflammatory effect.

Orphenadrine can be found in pharmacies or drugstores in the form of tablets or drops, with the trade names Dorflex, Doricin, Dorilax DT or Benoflex P, for example, for use in adults and should only be used with medical indication.

what is it for

Orphenadrine has a muscle relaxant and analgesic effect, being normally indicated for pain associated with muscle contractures, sprains or strains, and can also be used for tension headaches.

This medicine must be used as prescribed by a doctor, in doses and for the duration of treatment established by the doctor.

How to use

Orphenadrine in the form of tablets or drops must be taken orally, and the recommended doses for adults vary according to the other components of the formula and include:

  • Orphenadrine, Dipyrone and Caffeine Anhydrous (Dorflex or Doricin): the normally recommended doses are 1 to 2 tablets or 30 to 60 drops, 3 to 4 times a day;
  • Orphenadrine, acetaminophen and caffeine anhydrous (Doricin DT or Benoflex P): the normally recommended doses are 1 to 2 tablets, every 6 to 8 hours, outside of meal times. The maximum dose per day is 8 tablets and the treatment time should not exceed 3 days.

Orphenadrine should only be used with medical advice and with the doses and duration of treatment recommended by the doctor according to the condition being treated.

Possible side effects

The most common side effects that can occur during treatment with orphenadrine are dizziness, drowsiness, weakness, nausea, vomiting, dry mouth or constipation.

In addition, orphenadrine can cause side effects that need immediate medical attention such as heart palpitations, mental confusion, anxiety, tremor, fainting, hallucinations, pain or difficulty urinating.

Orphenadrine can also cause severe allergic reactions that need immediate medical attention. Therefore, you should stop treatment and seek the nearest emergency department if you experience symptoms such as difficulty breathing, feeling of a closed throat, swelling in the mouth, tongue or face, or hives. Know how to identify the symptoms of a severe allergic reaction.

who shouldn’t use

Orphenadrine should not be used by children, pregnant or breastfeeding women, or by people who have glaucoma, stomach or bowel obstruction, stomach ulcer, megaesophagus, prostate hypertrophy, myasthenia gravis, or bladder neck obstruction.

In addition, this medicine should not be used by people who are allergic to orphenadrine or other components of the formulas, such as dipyrone, paracetamol or anhydrous caffeine.

Orphenadrine should also not be used in cases of tachycardia, arrhythmia, prothrombin deficiency, coronary insufficiency or cardiac decompensation, unless recommended by a physician.

This medicine should not be used with alcohol, propoxyphene or phenothiazines.

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