HomeHealthHealthPiroxicam: what is it for, how to use it and side effects

Piroxicam: what is it for, how to use it and side effects

Piroxicam is the active ingredient of an analgesic, anti-inflammatory and antipyretic remedy indicated in the treatment of diseases such as rheumatoid arthritis and arthrosis, for example. This remedy is sold under the trade names Feldene or Floxicam, or in generic form such as piroxicam.

This medication can be found in the form of capsules, suppositories, soluble tablets, solution for intramuscular administration or gel for topical use and must be used with medical indication.

what is it for

Piroxicam is indicated for the treatment of inflammatory conditions such as acute gout, postoperative pain, post-traumatic injury, rheumatoid arthritis, menstrual cramps, osteoarthritis, arthritis, ankylosing spondylitis, and can be used by adults or children over 12 years old .

After use, pain and fever should subside in about 1 hour, lasting 2-3 hours.

How to use

This drug should only be used as medically indicated, and the dose depends on the form of presentation, which can be:

  • Oral use: the normally recommended dose of piroxicam is 1 tablet of 20 to 40 mg as a single daily dose, or 1 tablet of 10 mg twice a day;
  • Rectal use: the normally recommended dose is 20 mg piroxicam a day before bedtime;
  • Topical use: apply 1 g of the gel on the affected area, 3 to 4 times a day. Spread well until product residues have disappeared.

Piroxicam can also be used in an injectable form, which must be administered by a nurse, and 20 to 40 mg/2 mL per day are usually used in the upper quadrant of the gluteus.

Possible side effects

Side effects of piroxicam are most often gastrointestinal symptoms such as stomatitis, anorexia, nausea, constipation, abdominal discomfort, flatulence, diarrhea, abdominal pain, indigestion, gastrointestinal bleeding, perforation or ulcer.

Other symptoms that occur less frequently include swelling, headache, dizziness, drowsiness, insomnia, depression, nervousness, hallucinations, mood swings, nightmare, mental confusion, paresthesia or vertigo, anaphylaxis, bronchospasm, urticaria, angioedema, vasculitis and ” serum sickness”, onycholysis or alopecia.


Piroxicam should not be used by people who have an active peptic ulcer, or an allergy to piroxicam. This remedy should also not be used in the case of pain from coronary artery bypass graft surgery.

Furthermore, piroxicam should not be used together with aspirin or other non-steroidal anti-inflammatory drugs, or even in people who have developed asthma, nasal polyps, angioedema or urticaria after using aspirin or other non-steroidal anti-inflammatory drugs. kidney or liver failure.

This medication should not be used by children under the age of 12, pregnant or nursing women. In addition, piroxicam, like other non-steroidal anti-inflammatory drugs, can cause temporary infertility in some women.

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